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At present, China's pharmaceutical packaging industry already has more than 2,000 companies and can produce more than 30 varieties of pharmaceutical packaging materials in 6 categories, which can basically meet the needs of the domestic pharmaceutical industry, and annual sales have accounted for about 15% of the total pharmaceutical industry sales. Although China's pharmaceutical packaging has achieved certain achievements, there are still many problems. There is a clear gap between them and developed countries, and they need to be further efforts by colleagues in the industry.
Low drug packaging technology The drug packaging is an important part of drug production. For a long time, packaging has plagued the improvement of the preparation level in China. During the "Eighth Five-Year Plan" period, the State Pharmaceutical Administration gave great importance to pharmaceutical packaging. Since 1992, a licensing system has been implemented for packaging materials and containers that come into direct contact with drugs. The use of administrative measures to eliminate the straight-pin powder bottles, oral liquids for use in ampoule, non-foldable ampoules, and some natural rubber stoppers and non-open lids of pure aluminum. System (repair) set a batch of drug packaging materials standards. These measures have greatly promoted the improvement of pharmaceutical packaging. At the same time, with the gradual improvement of the market economic system, the majority of pharmaceutical companies also pay more and more attention to pharmaceutical packaging. At present, the total industrial output value of pharmaceutical packaging materials and containers has reached 9 billion yuan, accounting for 13.7% of the total value of the pharmaceutical industry. In spite of this, compared with developed countries, China's pharmaceutical packaging still has a considerable gap.
At present, the pharmaceutical packaging of some pharmaceutical companies in China still uses paper products that are prone to moisture and dust. However, the internationally advanced heat shrinkable film packaging has been used. This package has high strength, good transparency, good appearance, moisture resistance, dust resistance, and low cost. In the middle box packaging of 10 or 10 bottles of medicines as an example, the cost of box packaging in the heat shrinkable film is 0.03 yuan to 0.07 yuan each, and the carton cost is 0.5 yuan to 2 yuan each.
Nowadays, many of the domestically-made pharmaceutical tablets and capsules are bottle-shaped, and they can also be protected from light, moisture, and oxidation, but their technological content is not high. For special drug packaging with higher performance requirements for drug packaging materials, PVC hard sheets and PVC/PE composite hard films are required to be used as blister packs for blister packaging, which can prevent drugs from degrading mildew and extend the shelf life of drugs.
In pharmaceutical glass packaging, there is a certain gap between the material of glass and international similar products. Currently, pharmaceutical grade A materials are widely used in pharmaceutical glass in the world. The physical properties of these materials are more stable and can effectively protect the chemical properties of drugs. Moreover, the broken surfaces of broken bottles are smooth and free from subtle cracks. ratio.
In China, except for some joint ventures and large-scale state-owned enterprises using a small amount of Grade A materials, most enterprises still use Class B materials for pharmaceutical packaging, and pharmaceutical glass manufacturing enterprises still produce Class B materials. Experts believe that the causes and considerations of this phenomenon have arisen. At present, except for a few enterprises in China, only Vietnam and North Korea are still using Class B materials. Therefore, after passing away, class A materials have become the general trend to replace Class B materials. The relevant department predicts that China may cancel the use of Class B materials within five years.
The medicines containing infusion agents are mainly glass bottles, but the glass bottles are easily broken and reused during transportation, which may cause harm to human health. Some international developed countries have abandoned them. For example, Japan has replaced all plastic packaging.
There are two types of stoppers: butyl rubber stopper and natural rubber stopper. Butyl rubber is polymerized at ultra-low temperatures of around -95°C. Natural rubber is collected from rubber trees and processed through a series of processes. Experts believe that butyl rubber is superior to natural rubber stoppers in its chemical stability, hermeticity and bio-safety. It has been adopted by most enterprises, but some companies still use natural rubber stoppers.
After becoming alive, China's pharmaceuticals will melt into the global competition. With the improvement of people's living standards, the demand for packaging quality will also be higher and higher. It is imperative to improve pharmaceutical packaging.
The level of drug packaging design needs to be improved At present, there is still a certain gap between the design level and management system of China's pharmaceutical packaging and foreign countries, and the lack of competition in the international market. At the same time, it also faces the challenges and challenges of the internationally renowned crystal brand and high-quality packaging products. Therefore, domestic pharmaceutical companies should increase the design level of packaging and strengthen packaging management while paying attention to the quality of pharmaceutical packaging.
Drug packaging information is highly targeted, persistent, expressive, low-information, and slow. Therefore, in the process of drug packaging design, comprehensive consideration and clever choice should be made. To be on the package
Low drug packaging technology The drug packaging is an important part of drug production. For a long time, packaging has plagued the improvement of the preparation level in China. During the "Eighth Five-Year Plan" period, the State Pharmaceutical Administration gave great importance to pharmaceutical packaging. Since 1992, a licensing system has been implemented for packaging materials and containers that come into direct contact with drugs. The use of administrative measures to eliminate the straight-pin powder bottles, oral liquids for use in ampoule, non-foldable ampoules, and some natural rubber stoppers and non-open lids of pure aluminum. System (repair) set a batch of drug packaging materials standards. These measures have greatly promoted the improvement of pharmaceutical packaging. At the same time, with the gradual improvement of the market economic system, the majority of pharmaceutical companies also pay more and more attention to pharmaceutical packaging. At present, the total industrial output value of pharmaceutical packaging materials and containers has reached 9 billion yuan, accounting for 13.7% of the total value of the pharmaceutical industry. In spite of this, compared with developed countries, China's pharmaceutical packaging still has a considerable gap.
At present, the pharmaceutical packaging of some pharmaceutical companies in China still uses paper products that are prone to moisture and dust. However, the internationally advanced heat shrinkable film packaging has been used. This package has high strength, good transparency, good appearance, moisture resistance, dust resistance, and low cost. In the middle box packaging of 10 or 10 bottles of medicines as an example, the cost of box packaging in the heat shrinkable film is 0.03 yuan to 0.07 yuan each, and the carton cost is 0.5 yuan to 2 yuan each.
Nowadays, many of the domestically-made pharmaceutical tablets and capsules are bottle-shaped, and they can also be protected from light, moisture, and oxidation, but their technological content is not high. For special drug packaging with higher performance requirements for drug packaging materials, PVC hard sheets and PVC/PE composite hard films are required to be used as blister packs for blister packaging, which can prevent drugs from degrading mildew and extend the shelf life of drugs.
In pharmaceutical glass packaging, there is a certain gap between the material of glass and international similar products. Currently, pharmaceutical grade A materials are widely used in pharmaceutical glass in the world. The physical properties of these materials are more stable and can effectively protect the chemical properties of drugs. Moreover, the broken surfaces of broken bottles are smooth and free from subtle cracks. ratio.
In China, except for some joint ventures and large-scale state-owned enterprises using a small amount of Grade A materials, most enterprises still use Class B materials for pharmaceutical packaging, and pharmaceutical glass manufacturing enterprises still produce Class B materials. Experts believe that the causes and considerations of this phenomenon have arisen. At present, except for a few enterprises in China, only Vietnam and North Korea are still using Class B materials. Therefore, after passing away, class A materials have become the general trend to replace Class B materials. The relevant department predicts that China may cancel the use of Class B materials within five years.
The medicines containing infusion agents are mainly glass bottles, but the glass bottles are easily broken and reused during transportation, which may cause harm to human health. Some international developed countries have abandoned them. For example, Japan has replaced all plastic packaging.
There are two types of stoppers: butyl rubber stopper and natural rubber stopper. Butyl rubber is polymerized at ultra-low temperatures of around -95°C. Natural rubber is collected from rubber trees and processed through a series of processes. Experts believe that butyl rubber is superior to natural rubber stoppers in its chemical stability, hermeticity and bio-safety. It has been adopted by most enterprises, but some companies still use natural rubber stoppers.
After becoming alive, China's pharmaceuticals will melt into the global competition. With the improvement of people's living standards, the demand for packaging quality will also be higher and higher. It is imperative to improve pharmaceutical packaging.
The level of drug packaging design needs to be improved At present, there is still a certain gap between the design level and management system of China's pharmaceutical packaging and foreign countries, and the lack of competition in the international market. At the same time, it also faces the challenges and challenges of the internationally renowned crystal brand and high-quality packaging products. Therefore, domestic pharmaceutical companies should increase the design level of packaging and strengthen packaging management while paying attention to the quality of pharmaceutical packaging.
Drug packaging information is highly targeted, persistent, expressive, low-information, and slow. Therefore, in the process of drug packaging design, comprehensive consideration and clever choice should be made. To be on the package
