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Biosafety cabinets in Shanghai Xinzhuang are designed with advanced filtration systems for both intake and exhaust airflows, ensuring a safe working environment for laboratory personnel and protecting sensitive experiments from contamination. Among the various types, the first-class biosafety cabinet is unique in that it does not have an internal fan. Instead, it relies on an external duct system to circulate airflow. However, due to its limited ability to protect test samples or products, it is rarely used today.
The second-class biosafety cabinet, on the other hand, is the most commonly used type in laboratories worldwide. It features an inlet airflow through the front window, which helps prevent aerosols generated during microbial procedures from escaping into the lab environment. Unlike the first-class model, the incoming air is filtered before reaching the work area, reducing the risk of external contamination. A defining characteristic of Class II cabinets is the downward laminar airflow, created by a HEPA filter at the top of the unit. This continuous flow of clean air protects the test materials inside the cabinet from airborne particles and microbes.
According to industry standards, Class II cabinets are further divided into four subtypes—A1, A2, B1, and B2—based on their airflow velocity, exhaust method, and air recirculation pattern. Each type offers protection for the worker, the environment, and the test samples. For example, the A1 model requires a minimum airflow velocity of 0.38 m/s at the front window, with 70% of the air being recirculated through the HEPA filter and 30% exhausted after filtration. The A2 model has a slightly higher airflow requirement of 0.5 m/s, and also recycles 70% of the air while exhausting 30%. The negative pressure design in A2 cabinets ensures that any contaminated air remains contained within the cabinet.
The B1 and B2 models are more specialized. B1 cabinets are connected to the lab’s exhaust system and include a backup power supply to maintain negative pressure in case of a power outage. The B2 model is fully exhausted, with no internal air recirculation, making it ideal for handling hazardous chemicals and biological agents. These cabinets are completely sealed and often operate using glove ports, allowing researchers to handle samples without direct exposure. Test materials are transferred in and out via a double-door pass-through chamber, ensuring maximum containment.
For certain applications, such as when working with volatile or toxic chemicals, an A2 cabinet can be equipped with an external drain pipe cover. This feature includes an air inlet that helps balance the airflow within the cabinet, preventing over-pressurization. If a sealed duct is used without this inlet, the airflow could become too strong, potentially compromising the integrity of the work area. The inlet allows for room air to be drawn in, maintaining stability without affecting the cabinet's performance. However, this setup is only suitable for low concentrations of toxic substances.
Shanghai Xinzhuang specializes in producing high-quality biosafety cabinets that meet international safety standards. With a focus on innovation, reliability, and affordability, our products are trusted by labs around the world. Whether you're handling routine experiments or high-risk biological materials, our cabinets provide the necessary protection and peace of mind. Choose Shanghai Xinzhuang for superior performance, professional service, and long-term value. We welcome you to experience the difference.
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